Empiric therapy refers to the administration of treatment based on experience rather than knowledge of the exact cause of a disease. Differentiating the potential cause of cellulitis before initiating empiric therapy is important because of the emergence of bacterial resistance to antibiotics. Studies show that the emergence of methicillin-resistant Staphylococcus aureus (MRSA) and macrolide- or erythromycin-resistant Streptococcus pyogenes make it difficult to manage cellulitis (Sullivan & de Barra, 2018). Empiric treatment may only be beneficial to nonsevere cases that do not require hospitalization.
The most common cause of cellulitis is staphylococcus aureus making the selection of empiric therapy easy for non-complicated cases (Rosenthal & Burchum, 2020). The drug I would consider in this case is Flucloxacillin 500 mg PO qds. If the patient is allergic to penicillins, I would prescribe cephalexin 500 mg PO qds. These drugs are effective for the treatment of skin infections caused by gram-positive bacteria (Sullivan & de Barra, 2018). Because there are no signs of sepsis or necrotizing infection mentioned, the oral formulations will be preferred over parenteral therapy.
The monitoring parameters for this drug will include signs of penicillin allergy like anaphylaxis, stridor, angioedema, and immediate onset urticaria (Rosenthal & Burchum, 2020). If these are noticed, I would consider changing medication to second or third-generation cephalosporins. Side effects to monitor will include nausea, vomiting, diarrhea, boating, and indigestion (Rosenthal & Burchum, 2020). For drug efficacy, the patient should be able to respond to treatment within five days. The development of an abscess will indicate a worsening disease and this will require a change of medication and potential inpatient admission.
Medications like penicillins and cephalosporins are associated with diarrhea characterized by watery or loose stool three or more times a day while taking antibiotics. Clostridium defficile diarrhea is different because it is more severe, lasts for more than one day, and is associated with abdominal cramping, fever, and tenderness (Czepiel et al., 2018). Treatment may involve the use of antibiotics like vancomycin for at least 10 days and oral rehydration. In some cases, if there is severe damage, surgery may be recommended to remove affected sections of the intestines.
Czepiel, J., Dróżdż, M., Pituch, H., Kuijper, E. J., Perucki, W., Mielimonka, A., Goldman, S., Wultańska, D., Garlicki, A., & Biesiada, G. (2019). Clostridium difficile infection: review. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 38(7), 1211–1221. https://doi.org/10.1007/s10096-019-03539-6
Rosenthal, L., & Burchum, J. (2020). Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants-E-Book. Elsevier Health Sciences.
Sullivan, T., & de Barra, E. (2018). Diagnosis and management of cellulitis. Clinical Medicine (London, England), 18(2), 160–163.
- Fill out the matrix (excel file) to help you as you complete the assignment
- Explore The Technology Systems Offered By Nanthealth, A Provider Of “Telehealth” And Health Management Services Via The Following Link: Http://Nanthealth.Com/ Prepare A Brief (8-10 Slides) PowerPoint Presentation In Which You Do The Following
- Why Has Telehealth Adoption Taken So Long In The Health-Care Industry When Skype, Cell Phones, And Other Video Conferencing Applications Have Been Used In Personal And Business Interactions For Decades?
- Details: View The Scenario Called “Critical Decision Making For Providers
- Write A 2-3 Page Paper That Explains And Defends Your View On The Issue Of Whether Or Not Patients With No Other Treatment Options Have A Moral Right To Unproven Drugs.
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- Inter View With Pharmacist
- View the video “College of Nursing and Health Care Professions: Do we know what our future is?” for insight into the challenges of health care reform.
- Based on the “Case Study: Healing and Autonomy” and other required topic study materials, you will complete the “Applying the Four Principles: Case Study” document that includes the following
- African-American case study #2 Appalachian case study #1
- Interdisciplinary conflict and collaboration likely to be promoted by the Patient Protection and Affordable Care Act.
- Supreme court and the Patient Protection and Affordable Care Act (ACA) of 2010
- The Patient Protection and Affordable Care Act
- The implications of three different provisions of the Patient Protection and Affordable Care Act
- HCM590 module: Policy Summary and Assessment Paper; explain and assess the implications of three different provisions of the Patient Protection and Affordable Care Act.
- Patient Protection and Affordable Care Act
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