Researching Fluoxetine as an antidepressant
Antidepressants are an important part of treating depression, and they also try to improve the quality of life for people who are taking them, since most people with sadness can’t do things, deal with things, or feel pleasure. In the present health care system, there are many different antidepressants that work in different ways to treat depression. Fluoxetine is a serotonin reuptake inhibitor that is often used to treat depression. It can also be used to treat anxiety disorders like obsessive-compulsive disorder and eating disorders like bulimia. It is the drug of choice for this paper because we will be looking at its effects on neurotransmitter and receptor sites, desired behavioral effects, priority side effects, and percentage incidences of side effects.
Effects on places where neurotransmitters bind
Receptors are made to bind to neurotransmitter sites in a way that makes the neurotransmitter either more active or less active, depending on how the membrane is bound. If the membrane is bound by proteins, they are called ionotropic receptors, and they are activated by the opening and closing of specific channels, which changes the membrane potential of the postsynaptic cell.
Fluoxetine is well-known for its ability to stop seizures. This is because it acts as a positive modulator of GABA receptors, which stops Gamma-Aminobutyric acid from being released. It does stop neurotransmitter release by stopping serotonin transporter in a roundabout way. (Lazarevic et al., 2019).
Fluoxetine has some side effects.
Bastos, Guimaraes, and Trentini (2015) say that side effects are mostly caused by the drug’s pharmacological properties. According to Wang et al., these side effects have become much more common as the number of people taking antidepressants has risen dramatically. (2018). They can be different for each client because everyone reacts differently. Some of the side effects people might experience are lack of sleep, tremors, nervousness, blurred vision, and stomach problems like nausea and diarrhea (Micheli et al., 2018). Taking care of these side effects can also help the client get better quickly.
How to deal with side effects
Side effects do get in the way of patients’ normal lives, so they need to be managed well to improve the quality of care given to clients. Fear of side effects shouldn’t stop a client from taking their medicine as prescribed by their doctor, which highlights the importance of patient education. The side effects can be taken care of one at a time. For clients with insomnia, which means they have trouble falling asleep and staying asleep, and often have trouble falling asleep again, sedatives are a good solution. The client can also be told to move during the day and cut back on caffeine.People who have anxiety are often told to try relaxation methods or to get more exercise. Benzodiazepines and medications can be used together as a treatment as well. But stopping treatment is the most important thing to do if the situation gets worse.
Gastrointestinal: About 25% of patients report feeling sick, and their doctor can give them medicine to take at bedtime or with meals. Antidiarrheal drugs can be used to treat diarrhea, which happens in about 15% of people who take Fluoxetine. Most people who take antidepressants have blurred vision at some point. The woman does say that her eyes are itchy and red. To treat this successfully, it’s important to rule out any other possible causes of blurry vision. If the problem keeps happening, you could stop taking the medicine. Clients shouldn’t stop taking their medications without first talking to their doctors. Antidepressants often cause tremors that come and go, and the person taking them might also nod their head involuntarily. After a physical check to rule out any other causes of the tremors, a client’s medical history, including the medications they are currently taking, is often taken to rule out drug interactions that could cause the tremors. If a client is having tremors because of fluoxetine, the client’s medicine can be changed.
Client X, a 32-year-old mother of two daughters and a son who died recently, was admitted to the psychiatric unit against her will. She was brought there by her husband as part of her regular checkup and refill of Fluoxetine (20mg Per Oral 4 times a day) and other antidepressants she was taking. He said she was having stomach problems, diarrhea, not getting enough sleep, and being overly anxious as of late. Before she went to the hospital, the patient had stopped going to most social events and was often angry. She never liked the things she used to do with her family and friends, she had lost her appetite, and she had trouble sleeping. Before she got sick, she and her husband lost their son in a car accident. This made her symptoms worse. During a mental status test, the Psychiatrist on call found that she knew what time it was, where she was, and who she was with. Her memory was good, and she had good judgment. The main thing that worried the husband was that his wife was getting more anxious, having trouble sleeping, and having stomach problems.
Client X was taking Fluoxetine (20mg per oral dose, four times a day), which could have caused her stomach problems, like diarrhea, lack of sleep, and being too nervous, as reported by her husband. More questions were asked about how long it took for Client X to feel the other side effects, which were said to have started after three days. Before coming to the unit, the client took care of the signs and symptoms as best they could. Her husband got her medicine to help her deal with her diarrhea. The on-call doctor gave her some sleeping pills and drugs.
In conclusion, antidepressants are an important part of treating depression, and they aim to improve the quality of life for people who take them. This is because most depressed people can’t take part in or deal with events or feel pleasure. However, the side effects of serotonin reuptake inhibitors like Fluoxetine vary from person to person, and it is these side effects and how people deal with them that were the focus of this study. It’s sad, though, that clients don’t know much or anything about how to deal with these side effects. Fluoxetine clients should be taught more about how to deal with the side effects of the drug.
Bastos, A. G., Guimaraes, L. S. P., & Trentini, C. M. (2015). The efficacy of long-term psychodynamic psychotherapy, fluoxetine and their combination in the outpatient treatment of depression. Psychotherapy Research, 25(5), 612-624.
Lazarevic, V., Mantas, I., Flais, I., & Svenningsson, P. (2019). Fluoxetine suppresses glutamate-and GABA-mediated neurotransmission by altering SNARE complex. International journal of molecular sciences, 20(17), 4247.
Micheli, L., Ceccarelli, M., D’Andrea, G., & Tirone, F. (2018). Depression and adult neurogenesis: positive effects of the antidepressant fluoxetine and of physical exercise. Brain research bulletin, 143, 181-193.
Wang, S. M., Han, C., Bahk, W. M., Lee, S. J., Patkar, A. A., Masand, P. S., & Pae, C. U. (2018). Addressing the side effects of contemporary antidepressant drugs: a comprehensive review. Chonnam medical journal, 54(2), 101-112.
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