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Question: In what direction does DNA synthesis occur? Is there an
advantage to having DNA synthesis go in t…


In what direction does DNA synthesis occur? Is there an
advantage to having DNA synthesis go in this direction? Please
explain. Why is the presence of a hydroxyl group on the 2’ carbon
in ribose thought to be significant in the direction of DNA
synthesis?

What does it mean when we say DNA structure is
anti-parallel?

Explain why polymerases for both RNA and DNA synthesis have an
inherent error rate of 10-4. Why can’t the error rate be
lower? What function associated with DNA synthesis lowers the error
rate and serves as a proof-reading function?

What function does the 3’-5’ exonuclease serve? If a mutation
caused this function to decrease, what do you think would
happen?

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